Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | TMEFF1 |
| Gene Name: | TMEFF1 |
| Protein Full Name: | Tomoregulin-1 |
| Alias: | C9orf2; H7365; Teff1; Tmeff1; Transmembrane protein with egf-like and two follistatin-like domains 1 |
| Mass (Da): | 40934 |
| Number AA: | 380 |
| UniProt ID: | Q8IYR6 |
| Locus ID: | 8577 |
| COSMIC ID: | TMEFF1 |
| Gene location on chromosome: | 9q31 |
| Number of cancer specimens: | 19626 |
| Percent of cancer specimens with mutations: | 0.31 |
| Commentary on involvement of protein in cancer: | May inhibit NODAL and BMP signaling during neural patterning By similarity. May be a tumor suppressor in brain cancers. |