Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: RASGRP2
Gene Name: RASGRP2
Protein Full Name: RAS guanyl-releasing protein 2
Alias: Calcium and DAG-regulated guanine nucleotide exchange factor I; CALDAG-GEFI; CDC25L; GRP2; Guanine exchange factor MCG7; RAS guanyl nucleotide-releasing protein 2; RAS guanyl releasing protein 2; RAS guanyl releasing protein 2 (calcium and DAG-regulated)
Mass (Da): 69248
Number AA: 609
UniProt ID: Q7LDG7
Locus ID: 10235
COSMIC ID: RASGRP2
Gene location on chromosome: 11q13
Number of cancer specimens: 19718
Percent of cancer specimens with mutations: 0.52


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