Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CDK6 |
| Gene Name: | CDK6 |
| Protein Full Name: | Cell division protein kinase 6 |
| Alias: | CRK2; Cyclin-dependent kinase 6; EC 2.7.11.22; Kinase Cdk6; PLSTIRE; Serine/threonine protein kinase PLSTIRE |
| Mass (Da): | 36938 |
| Number AA: | 326 |
| UniProt ID: | Q00534 |
| Locus ID: | 1021 |
| COSMIC ID: | CDK6 |
| Gene location on chromosome: | 7q21.2 |
| Number of cancer specimens: | 20735 |
| Percent of cancer specimens with mutations: | 0.23 |
| Found in amplified chromosomal regions in human cancers: | Gliomas (5%) |
| Normal role description: | CDK6 is a protein-serine/threonine kinase. |