Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | SRPK2 |
| Gene Name: | SRPK2 |
| Protein Full Name: | Serine/threonine-protein kinase SRPK2 |
| Alias: | EC 2.7.11.1; Serine/arginine-rich protein-specific kinase 2; Serine/threonine-protein kinase SRPK2; SFRS protein kinase 2; SFRSK2; SR-protein-specific kinase 2 |
| Mass (Da): | 77543 |
| Number AA: | 688 |
| UniProt ID: | P78362 |
| Locus ID: | 6733 |
| COSMIC ID: | SRPK2 |
| Gene location on chromosome: | 7q22-q31.1 |
| Cancer protein type: | UNCLEAR |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | UNCLEAR |
| Number of cancer specimens: | 20731 |
| Percent of cancer specimens with mutations: | 0.57 |
| Normal role description: | Phosphorylates SFRS1 and SFRS2 on serine residues. Involved in spliceosome assembly and splicing factor trafficking. |