Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | RPL26 |
| Gene Name: | RPL26 |
| Protein Full Name: | 60S ribosomal protein L26 |
| Alias: | RL26 |
| Mass (Da): | 17258 |
| Number AA: | 145 |
| UniProt ID: | P61254 |
| Locus ID: | 6154 |
| COSMIC ID: | RPL26 |
| Gene location on chromosome: | 17p13.1 |
| Cancer protein type: | TSP |
| Effect of cancer mutation on protein: | UNCLEAR (probably LOSS) |
| Effect of active protein on cancer: | INHIBIT |
| Number of cancer specimens: | 19718 |
| Percent of cancer specimens with mutations: | 0.09 |
| Mutations observed as inherited: | NA |
| Found in amplified chromosomal regions in human cancers: | NA |
| Deregulated in translocations: | NA |
| Deregulated by viral insertion: | NA |
| Transduced into viral genome: | NA |
| Gene undergoes hypermethylation: | NA |
| Normal role description: | RPL26 is a ribosomal protein part of the 60S ribosome subunit. It may have a role in enhancing p53 translation and stability. |