Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: COPS2
Gene Name: COPS2
Protein Full Name: COP9 signalosome complex subunit 2
Alias: ALIEN; COP9 constitutive photomorphogenic homologue subunit 2; COP9 constitutive photomorphogenic homologue subunit 2 (Arabidopsis); CSN2; JAB1-containing signalosome subunit 2; SGN2; Signalosome subunit 2; Thyroid receptor interacting protein 15; Thyroid receptor-interacting protein 15; TRIP15
Mass (Da): 51597
Number AA: 443
UniProt ID: P61201
Locus ID: 9318
COSMIC ID: COPS2
Gene location on chromosome: 15q21.1
Number of cancer specimens: 19718
Percent of cancer specimens with mutations: 0.41
Normal role description: Corepressor for nuclear hormone receptor


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