Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: HOXD11
Gene Name: HOXD11
Protein Full Name: Homeobox protein Hox-D11
Alias: Homeo box D11; Homeobox D11; HOX4; HOX4F; Hox-4F
Mass (Da): 35500
Number AA: 338
UniProt ID: P31277
Locus ID: 3237
COSMIC ID: HOXD11
Gene location on chromosome: 2q31.1
Number of cancer specimens: 19535
Percent of cancer specimens with mutations: 0.22
Commentary on involvement of protein in cancer: Homeobox protein Hox-D11 sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.


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