Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | GSTP1 |
| Gene Name: | GSTP1 |
| Protein Full Name: | Glutathione S-transferase P |
| Alias: | FAEES3; glutathione S-transferase pi 1; GST class-pi; GST3; GSTP1-1; GTP |
| Mass (Da): | 23356 |
| Number AA: | 210 |
| UniProt ID: | P09211 |
| Locus ID: | 2950 |
| COSMIC ID: | GSTP1 |
| Gene location on chromosome: | 11q13.2 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.19 |
| Gene undergoes hypermethylation: | Breast, liver and prostate tumours. |
| Normal role description: | Mutagen inactivator. Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. |