Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | CAMTA2 |
| Gene Name: | CAMTA2 |
| Protein Full Name: | Calmodulin-binding transcription activator 2 |
| Mass (Da): | 131530 |
| Number AA: | 1202 |
| UniProt ID: | O94983 |
| Locus ID: | 23125 |
| COSMIC ID: | CAMTA2 |
| Gene location on chromosome: | 17p13.2 |
| Number of cancer specimens: | 19625 |
| Percent of cancer specimens with mutations: | 0.91 |
| Normal role description: | CAGE1 is a nuclear localized protein. In normal tissue CAGE1 expression is restricted to the testis while high levels of expression can be detected in cancer tissues. The exact function of CAGE1 in the cell is still relatively unknown. It has been implicated in lung, cervix and stomach cnacers and may be associated with tumour progression. |
| Commentary on involvement of protein in cancer: | No entry in Atlasgeneticsoncology.org |