Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: TRIM37
Gene Name: TRIM37
Protein Full Name: E3 ubiquitin-protein ligase TRIM37
Alias: KIAA0898; MUL; Mulibrey nanism protein; POB1; RING-B-box-coiled-coil protein; TEF3; TRI37; Tripartite motif-containing 37; Tripartite motif-containing protein 37
Mass (Da): 107887
Number AA: 964
UniProt ID: O94972
Locus ID: 4591
COSMIC ID: TRIM37
Gene location on chromosome: 17q23.2
Cancer protein type: UNCLEAR
Effect of cancer mutation on protein: UNCLEAR
Effect of active protein on cancer: UNCLEAR
Number of cancer specimens: 20239
Percent of cancer specimens with mutations: 0.76
Normal role description: Involved in developmental patterning and oncogenesis. Might be involved in protein-protein interactions and/or protein-nucleic acid interactions.


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