Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: Smad6
Gene Name: SMAD6
Protein Full Name: Mothers against decapentaplegic homolog 6
Alias: HSMAD6; HsT17432; MADH6; MADH7; Mothers against decapentaplegic 6; Mothers against DPP 6; SMAD 6; SMAD family member 6
Mass (Da): 53497
Number AA: 496
UniProt ID: O43541
Locus ID: 4091
COSMIC ID: SMAD6
Gene location on chromosome: 15q22.31
Number of cancer specimens: 19905
Percent of cancer specimens with mutations: 0.25


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