Cancer Protein Description

This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.


Protein Name: SH2B2
Gene Name: SH2B2
Protein Full Name: SH2B adapter protein 2
Alias: Adapter protein with pleckstrin homology and Src homology 2 domains; Adaptor protein with pleckstriny and src; SH2 and PH domain-containing adapter protein APS; SH2B adaptor protein 2; SH2B2
Mass (Da): 67738
Number AA: 632
UniProt ID: O14492
Locus ID: 10603
COSMIC ID: SH2B2
Gene location on chromosome: 7q22.1
Number of cancer specimens: 19535
Percent of cancer specimens with mutations: 0.28
Commentary on involvement of protein in cancer: No entry found in sangercosmic database.


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