Cancer Protein Description
This report provides a detailed description of a selected cancer protein with information collected from various sources, including UniProt, the Wellcome Trust Sanger Institute’s Catalogue of Somatic Mutations in Cancer (COSMIC), and the Atlas of Genetics and Cytogenetics in Oncology and Haematology.
| Protein Name: | NBAS |
| Gene Name: | NBAS |
| Protein Full Name: | Neuroblastoma-amplified sequence |
| Alias: | Neuroblastoma amplified sequence; Neuroblastoma-amplified |
| Mass (Da): | 268571 |
| Number AA: | 2371 |
| UniProt ID: | A2RRP1 |
| Locus ID: | 51594 |
| COSMIC ID: | NBAS |
| Gene location on chromosome: | 2p24.3 |
| Cancer protein type: | ?OP |
| Effect of cancer mutation on protein: | UNCLEAR |
| Effect of active protein on cancer: | PROMOTES |
| Number of cancer specimens: | 19626 |
| Percent of cancer specimens with mutations: | 1.92 |
| Normal role description: | Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Role in normal cell not well understood. Up-regulated together with N-myc in some neuroblastoma cell lines |